Gemcitabine HCl ( —— )

Catalog No. M10836 CAS No. 122111-03-9

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Product Name

Gemcitabine HCl
Note

Research use only, not for human use.
Brief Description

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
Description

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

DNA synthesis (BxPC3 cells); DNA synthesis (Capan2 cells); DNA synthesis (MIAPaCa2 cells); DNA synthesis (PANC1 cells)
Research Area

Cancer
Indication

——

CAS Number

122111-03-9
Formula Weight

299.66
Molecular Formula

C9H11F2N3O4.HCI
Purity

>98%(HPLC)
Solubility

DMSO:<1 mg/mL (<1 mM); Ethanol:<1 mg/mL (<1 mM); Water：19 mg/mL (63.4 mM)
SMILES

Cl.NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F |r,c:6,t:1|
Chemical Name

——

1.Shi X, et al. Oncology. 2002, 62(4), 354-362.

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